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What is an acanthosis?

What is an acanthosis? Here are some definitions.

Noun
  1. (medicine) A benign abnormal thickening of the stratum spinosum, or prickle cell, layer of the epidermis.[First attested in the late 19th century.]
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Glycogenic acanthosis is a common degenerative condition characterized by accumulation of cytoplasmic glycogen in the squamous epithelium of the esophagus.
Patients are often concerned about the physical manifestations of this disorder, including virilization and acanthosis nigricans, and may be less aware of systemic problems.
There were also esophageal glycogenic acanthosis and hyperplastic polyposis in the antrum accompanied by Helicobacter pylori-related gastritis.
Two larger pieces consisted of clearly nondysplastic squamous epithelium with glycogenic acanthosis.
Hi stological examination of the lesions typically reveals hyperkeratosis with or without parakeratosis, acanthosis, and enlargement of the rete ridges.
Obesity, acne, hirsutism, and acanthosis nigricans may be signs of polycystic ovary syndrome or diabetes mellitus.

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