In third-world countries, it has been used to treat onchocerciasis in pregnant and nursing women, with no teratogenic effects observed. |
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However, treatment needs to be individualized, weighing the possible teratogenic risks against the benefits of decreased transmission. |
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There was no history of familial dwarfism or known exposure to teratogenic drugs. |
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The catalog provides a source of reference for teratologists wishing knowledge of the literature dealing with a particular teratogenic agents. |
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Women on anticonvulsant medication should be switched to the least teratogenic drug, and the smallest clinically effective dose. |
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This class of drugs should be avoided in pregnancy because of teratogenic effects. |
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Because of the known teratogenic side effects of high-dose vitamin A, there is limited application of retinoic acid for women of reproductive age. |
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The newer generation of antiepileptic drugs is not teratogenic in animals, but there is not sufficient reporting in human pregnancy experience to accurately portray risk. |
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It has been shown to be teratogenic and carcinogenic in rodents. |
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In another testing laboratory, formoterol fumarate was shown to be teratogenic in rats and rabbits. |
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Zileuton and zafirlukast should be avoided during pregnancy because they are teratogenic or fetotoxic in animals. |
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Related compounds, such as trifluoperazine and perphenazine, also may have low teratogenic risk, although they are not as well studied as phenothiazine chlorpromazine. |
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Ticlid is fetotoxic in mice, rabbits, and rats, but is not teratogenic. |
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Another anthelmintic, pyrantel, rated C, is not teratogenic in rats or rabbits, but there are no human reports of its use in pregnancy or lactation. |
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