| This would be analogous to other flavoproteins such as mercuric ion reductase, lipoamide dehydrogenase, and thioredoxin reductase. |
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| The concentration of androgen receptor and 5 reductase activities in frontal hair follicles is greater than in occipital follicles. |
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| These enzymes are thioredoxin reductase and glutathione reductase respectively. |
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| Total tropinone reductase activity was measured photometrically by NADPH consumption with tropinone as substrate. |
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| The authors also thank their colleague for sending them the coordinates of mercuric ion reductase. |
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| Sulphate reduction is initiated and carried out by the enzyme APS reductase in leaf and root plastids. |
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| The enzymatic mechanism of detoxification involves dehydroascorbate reductase, glutathione reductase and other enzymes. |
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| The polyol pathway uses the enzyme aldose reductase to convert glucose to sorbitol. |
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| Energy-related parameters measured were fermentation end-products, respiratory rate, ATP, adenylate energy charge, nitrate reductase activity and biomass. |
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| In patients with normal reductase function, significant production of methemoglobin would require even larger doses of isosorbide-5-mononitrate. |
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| The examples provided in this study focus on the use of HMG CoA reductase inhibitors in the ODB program. |
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| Transgenic yellow poplar plants overexpressing the bacterial gene encoding mercuric reductase were developed for the phytoremediation of mercury pollution. |
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| Nitrate reduction is catalysed by nitrate reductase and nitrite reductase. |
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| Use of 5-ethynyluracil in the manufacture of a medicament for use as a uracil reductase inactivator in cancer chemotherapy. |
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| Phase 1 clinical trials provide evidence that the nanorobots can silence a gene that makes an essential enzyme called ribonucleotide reductase. |
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| It acts by inhibiting an isomerase and a reductase enzyme in sterol biosynthesis in fungal membranes. |
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| The risk of myopathy is increased by high levels of HMG-CoA reductase inhibitory activity in plasma. |
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| It is noteworthy that the values obtained for the wild type in cells grown in the presence of molybdate are lower for nitrate reductase and nicotinate hydroxylase. |
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| There is limited evidence that inhibitors of HMG-CoA reductase may augment residual DHCR7 activity of some mutants leading to increase in the plasma cholesterol levels. |
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| Methotrexate works by blocking the action of a key enzyme, dihydrofolate reductase, which cancer cells require to thrive. |
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| Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress. |
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| The gene, pyrroline-5-carboxylate reductase 1, carries out the final step of proline synthesis. |
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| Erythrocyte aldose reductase activity and sorbitol levels in diabetic retinopathy. |
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| Experimental parameters included serum lipid levels, hepatic lipid peroxidation, levels of HMG-CoA reductase and antioxidant profiles. |
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| Diplopia, blepharoptosis, and ophthalmoplegia and 3-hydroxy-3-methyl-glutaryl-CoA reductase inhibitor use. |
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| Nitrofuran drugs as common subversive substrates of Trypanosoma cruzi lipoamide dehydrogenase and trypanothione reductase. |
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| A monoclonal antibody which is specifically reactive with a human ribonnucleotide reductase R2 subunit and which is capable of inhibiting ribonucleotide reductase activity. |
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| We will also examine every portion of the HMG reductase gene in search of additional genetic anomalies which would explain why certain persons are genetically at higher risk to develop the disease. |
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| The active form of lovastatin is a specific reversible inhibitor of HMG-CoA reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate. |
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| In the renal tubular epithelium, a considerable proportion of mesna disulphide is again reduced to a free thiol compound, presumably by mediation of glutathione reductase. |
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| Dissimilatory arsenate reductase activity and arsenate-respiring bacteria in bovine rumen fluid, hamster feces, and the termite hindgut. |
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| Use of a compound which inhibits steroid 5-alpha reductase activity without antagonising the androgen receptor in the manufacture of a medicament for use in the treatment of human prostatic adenocarcinoma. |
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| Rare cases of rhabdomyolysis with acute renal failure secondary to myoglobinuria have been reported with CRESTOR and with other HMG-CoA reductase inhibitors. |
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| However, an increase in the incidence of myositis and myopathy has been seen in patients receiving other HMG-CoA reductase inhibitors together with these medicines. |
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| Method for lowering the content of nitrates stored in a plant, characterized in that an overexpression of nitrate reductase is induced in the plant. |
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| Effect of hydroxymethyl glutaryl coenzyme a reductase inhibitor therapy on high sensitive C-reactive protein levels. |
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| Effect of Hydroxymethyl glutarly coenzyme A reductase inhibitor therapy on high sensitive C-reaktive protein levels. |
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| In the intestine, the maturation arrest enteritis seen in the dog was similar to that described in dogs given dihydrofolate reductase inhibitors and nucleoside analogs. |
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| One mechanism of action of proguanil, via its metabolite cycloguanil, is inhibition of dihydrofolate reductase, which disrupts deoxythymidylate synthesis. |
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| The researchers discovered that chlorophyllin reduces an enzyme needed for DNA synthesis known as ribonucleotide reductase. |
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| Ribonucleotide reductase catalyzes the critical conversion of ribonucleotides to deoxyribonucleotides in all organisms. |
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| These data validate mangosteen as an abundant natural source of potent aldose reductase inhibitors. |
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| Rationally designed selective inhibitors of trypanothione reductase phenothiazines and related tricyclics as lead structures. |
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| Cystathionine beta-synthase or thermolabile methylenetetrahydrofolate reductase enzymes, and vitamins like B12, B6 and folic acid are the cofactors in the metabolism of Hcy. |
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| In this study, we report for the first time the effects of these natural compounds on ribonucleotide reductase metabolism in human HL-60 promyelocytic leukemia cells. |
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| Interactions of oxaloacetate with Escherichia colt fumarate reductase. |
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| It is reduced by nitrate reductase in assimilatory or dissimilatory way. |
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| The aldose reductase inhibitory effects of the compounds were determined, and 3-isomangostin was found to be the most active against the enzyme when tested in vitro. |
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| It has been suggested that ritonavir reduces the redox potential of the hemoprotein CYP3A4 and prevents it reduction by its redox partner cytochrome P450 reductase. |
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| Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity. |
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| Normal mice gained weight and developed fatty liver and insulin resistance, but mice lacking aldose reductase showed less weight gain and less-severe related conditions. |
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| Enzymes such as sulphur transferase and sulphur reductase may be involved in contributing the methane thiol group on the indole ring of tyrindoxyl sulfate. |
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| Reductase nucleic acids and their encoded polypeptide were isolated and identified. |
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| The Synthesis of the Dissimilatory Nitrate Reductase Under Aerobic Conditions in a Number of Denitrifying Bacteria Isolated from Activated Sluge and Drinking Water. |
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