How to use preclinical in a sentence

Looking for sentences and phrases with the word preclinical? Here are some examples.

Sentence Examples Electronic databases will continue to grow in size and cover medicine, nursing, dentistry, veterinary medicine and the preclinical sciences. I was 20, a first year preclinical student, awaiting surgery for a large hiatus hernia. Specifically, the sojourn time of the preclinical duration is modeled by the tumor growth rate or, equivalently, by the tumor doubling time. They also do the vast majority of drug development, from preclinical animal studies through human clinical trials, and bear the economic risk. Beyond the fear and uncertainty about this illness, the diabetes study has been condemned for insufficient preclinical research. Alzheimer's disease is characterised by a long preclinical period during which cognitive deficits are detectable. Between 1991 and 1995, some students were sent for preclinical training in Australia and South Africa as well as Britain. These are proving particularly effective for treating cancer in preclinical models. This provides a wide therapeutic window, especially as groups at risk are identified earlier and preclinical diagnosis becomes feasible. These findings suggest a need for in vivo studies with this combination in preclinical prostate cancer models. Moreover, we screened for preclinical signs and not for signs of overt lung disease. It covers 4300 journals devoted to medicine, nursing, dentistry, veterinary medicine, healthcare systems, and the preclinical sciences. He said he hopes the model will be useful in preclinical testing of possible preventive therapies before they are given to human subjects. A number of such vectors are currently being developed and tested in preclinical and early phase clinical trials. The authors called for greater use of systematic reviews in preclinical drug evaluation. Drug Reports are summaries of drugs in development from preclinical to launched drugs. Only five compounds out of 5,000 in preclinical tests get as far as human trials. In preclinical testing these vectors were highly effective against cancerous tumors and did not harm normal tissues. Some recent reviews are listed here on general properties of porphyrins as sensitizers and on their preclinical and clinical tests. In 2001 and 2002 we completed all of our clinical trials, our preclinical trials, and the animal work and bench work on the product. Show More Sentences Several drugs are currently under preclinical and early phase clinical study. The grant will fund two clinical trials, three preclinical research studies, and a training program in gene therapy. In preclinical trials, it has been shown to reduce the incidence of diabetes in animals, apparently by down-regulating the immune response. Today, gross anatomy is taught in a preclinical dissection course for second year medical students. Medical students with high preclinical and clinical grade point averages were, surprisingly, more likely to express an external orientation. She completed her preclinical training at technical colleges before going to Leeds, where she met her husband, Benno Pollak. After graduation, he decided to follow a growing conviction that his life should be in medicine, and he moved to Oxford for preclinical studies. The success of preclinical microdialysis indicates ample opportunity for clinical neuropharmacological studies. It's sufficient to say that preclinical medical students aren't the only people a little enamored with this disease. Diseases with long preclinical phases are more likely to be detected by screening. He trained at Edinburgh because Guy's would not recognise his preclinical year at Witswattersrand University. In preclinical and clinical studies at cytostatic doses, paclitaxel has demonstrated promising results for reducing the processes leading to restenosis. Data from a screening study showed that a screening interval of nine months was too long, and from this it was assumed that bladder cancer has a brief preclinical duration. Mercury is neurotoxic, and even in people with low level chronic exposure, subtle preclinical effects on symptoms, mood, motor function, and cognition have been identified. Another small preclinical study demonstrated improved tumor response for human rectal-carcinoma xenografts treated with PDT under hyperbaric oxygen. Disulfiram has been used as an antialcoholism drug for over 60 years with preclinical and clinical safety data available. The strains to use must be selected with care and based on extensive preclinical. Emergency medicine in Switzerland encompasses preclinical emergency medicine outside hospitals and clinical emergency medicine in hospital. Although the preclinical data have been promising, human studies using vitamin A or retinoids as chemopreventive agents have been largely disappointing. Our haemostatic agent is in preclinical stage and it is our objective to obtain regulatory approvals for both products at the same time. Show More Sentences We are currently conducting pharmacokinetic studies on PPL-100 and other preclinical work on this compound is nearing completion. Ambrilia is currently setting up a preclinical program for anticancer agents to be integrated into the TVT delivery system. The neurotherapy pipeline also includes preclinical gene-based therapeutics for vision loss, motor neuron disease and nerve repair. Of the 5,000 10,000 compounds that are screened, approximately 250 will enter preclinical testing, and 5 will enter clinical testing. All of the products of the Company are subject to preclinical and clinical studies. Founded in 2005, the company has a pipeline of three products, of which one is in development and two at the end of preclinical trials. Therefore, standardized protocols and measures of effectiveness need to be adopted at the preclinical and clinical stages of vaccine development. Theratechnologies has peptides in discovery and preclinical development for this indication. A current classification divides genetic tests into preclinical or presymptomatic tests and tests for the assessment of genetic susceptibility. This model is intended to enhance management of the complex processes involved in discovery, preclinical development and clinical research. Neurochemical approaches may generate novel biomarkers of mercury exposure and preclinical effects in wildlife. The Company must complete preclinical studies in order to file a CTA in Canada and an IND in the United States. Elevating plasma cortisol levels, either by exogenous administration or stress, facilitates the acquisition of stimulant administration in preclinical rodent models. There is ample evidence of a prolonged preclinical phase in lung cancer. As well, we intend to fund the advancement of additional drug candidates into preclinical development. It also has limited internal resources and capacity to perform preclinical studies and clinical trials. With a unique preclinical profile, its development is focused on FGFR driven diseases. The investigators are also working on synthesizing new radiotracers, contrast agents, and radiosensitivity agents in preclinical and clinical testing to validate them with a view to marketing. Bambal joins Absorptions Systems with considerable pharmaceutical industry experience in drug discovery and preclinical development. WuXi has been a leader in providing preclinical and clinical medical device testing services in the United States for many years. Show More Sentences A limit should be specified for the antipode and this limit should be qualified through the levels found in batches used in preclinical and clinical studies. Theratechnologies also has well-equipped discovery and preclinical research laboratories which include two cell culture rooms and several chemical hoods. During the past quarter, we also continued preclinical studies for our HDAC inhibitors for Huntington's disease, a fatal genetic disorder with no current therapies. Medivir presented preclinical data on two candidate drugs from its cathepsin K inhibitor program in a poster session during the ASBMR meeting. Neuropathies had not been observed in preclinical or clinical studies, but they began to appear in the postmarketing period. Such a vaccination has already demonstrated increased in-vivo clonal expansion and maintenance of adoptively transferred tumor-antigen specific cytotoxic lymphocytes in preclinical models. There is a paucity of preclinical models that simulate the development of ovarian tumors in humans. All of the Company's molecules are in preclinical studies, except tesamorelin for the treatment of HIV-associated lipodystrophy that is in Phase 3 clinical studies. Previously disclosed MGCD290 preclinical data demonstrated that the molecule synergizes and potentiates azole activity both in vitro and in vivo against key fungal pathogens such as Aspergillus and various Candida species. Coarse punctation and mosaicism tend to occur in more severe neoplastic lesions such as CIN 2, CIN 3 lesions and early preclinical invasive cancer. On the basis of the preclinical pharmacology studies sedation, constipation, mydriasis, ataxia, respiratory depression, and elevated body temperature would be anticipated side effects of tramadol. There was agreement that transplantation of solid, vascularized organs is still premature and requires significant preclinical research before clinical trials proceed. The Company's employees have expertise in various biotechnology sectors such as the development of peptides, synthesis, toxicology, immunology, regulatory and the conduct of preclinical and clinical studies. The sensitivity of this system surpasses competitors' devices on the preclinical market because it can detect lower concentrations of signals deeper inside the body. In other cases, however, such as when a detectable preclinical phase of a cancer is not known or there is no effective treatment for the cancer, screening programs may not be beneficial. It expects to incur further losses during the next several years resulting from the continuation of our ongoing clinical trials and preclinical development activities. This compound is at the preclinical stage. This new antibody is currently in preclinical development. On average, only 5 in 5 000 compounds pass on from the preclinical testing phase to clinical trials, and only one of these five is finally approved. In 2005, major milestones were reached in PPL-100's development program with the completion of the preclinical development and the beginning of the first-in-man Phase I clinical trial. Show More Sentences Ambrilia continues exploring the possibilities of its TVT Technology and is currently setting up a preclinical program for anti-cancer agents to be integrated into the TVT delivery system. In preclinical trials, the aminopyrazole series exhibited good antiparasitic activity, and are expected to be highly safe and effective. The milestone being announced today relates to the second preclinical milestone for one of the checkpoint protein candidates. The project is being directed by Su and Bert Pronk, SuviCa s vice president of preclinical development. The development program also includes ONX 0914, an immunoproteasome inhibitor with activity in preclinical models of autoimmune disorders. Specific analogs of these hepatoselective insulins have undergone preclinical and initial Phase I clinical proof of concept testing in humans. The Company is currently evaluating AnergiX compounds in preclinical studies to ascertain their efficacy in inducing anergy or non responsiveness in disease-causing T cells. Accium's accelerator mass spectrometry services has primarily aided the investigation of drug candidates in preclinical and early clinical development. Novavax Inc said data from a preclinical trial showed very low doses of its avian flu vaccine still prevented the virus from infecting tested ferrets. In addition, PER has shown broad-spectrum antiepileptic activity when administered orally in preclinical animal models, including antimyoclonic activity. Tmax, aTyr's first program, is a preclinical replacement protein candidate with a novel thrombopoietic activity for the treatment of thrombocytopenia. Areas explored include preclinical and clinical pharmacokinetics, as well as toxicology and safety of flavonoids and their possible drug interactions. Results of preclinical trials performed on animals showed low ghrelin levels result in reduced cholesterol and sugar levels, regardless of high-fat diets. The early phase findings also showed prolonged survival in an intracerebral BTIC xenograft preclinical model of human GBM when delivered in combination with temozolomide. In a preclinical model of efficacy, PRS-080 administration showed complete inhibition of hepcidin-induced hypoferremia in a dose-dependent manner. Jaen brings more than 20 years of expertise in drug discovery, chemistry and preclinical development across a number of therapeutic areas to ChemoCentryx. However, owing to their high toxicities, colchicine and thiocolchicine are still in preclinical trials to determine their potential anti-tumor activity. On the basis of preclinical evaluation in animal models of human conditions, one might expect a Delta agonist to show effect in inflammatory pain, among other pain conditions. Examples from Classical Literature Dietary supplementation with whole blueberries in a preclinical study resulted in a reduction in glucose concentrations over time. Find more words! Another word for Opposite of Meaning of Rhymes with Sentences with Find word forms Translate from English Translate to English Words With Friends Scrabble Crossword / Codeword Words starting with Words ending with Words containing exactly Words containing letters Pronounce Find conjugations Find names From Afrikaans From Albanian From Amharic From Arabic From Armenian From Azerbaijani From Basque From Belarusian From Bengali From Bosnian From Bulgarian From Catalan From Cebuano From Chichewa From Chinese From Corsican From Croatian From Czech From Danish From Dutch From Esperanto From Estonian From Farsi From Filipino From Finnish From French From Frisian From Galician From Georgian From German From Greek From Gujarati From Haitian Creole From Hausa From Hebrew From Hindi From Hmong From Hungarian From Icelandic From Igbo From Indonesian From Irish From Italian From Japanese From Javanese From Kannada From Kazakh From Khmer From Korean From Kurdish From Kyrgyz From Lao From Latin From Latvian From Lithuanian From Luxembourgish From Macedonian From Malagasy From Malay From Malayalam From Maltese From Maori From Marathi From Mongolian From Burmese From Nepali From Norwegian From Polish From Portuguese From Punjabi From Romanian From Russian From Samoan From Scots Gaelic From Serbian From Sesotho From Shona From Sinhala From Slovak From Slovenian From Somali From Spanish From Sundanese From Swahili From Swedish From Tajik From Tamil From Telugu From Thai From Turkish From Ukrainian From Urdu From Uzbek From Vietnamese From Welsh From Xhosa From Yiddish From Yoruba From Zulu To Afrikaans To Albanian To Amharic To Arabic To Armenian To Azerbaijani To Basque To Belarusian To Bengali To Bosnian To Bulgarian To Catalan To Cebuano To Chichewa To Chinese To Corsican To Croatian To Czech To Danish To Dutch To Esperanto To Estonian To Farsi To Filipino To Finnish To French To Frisian To Galician To Georgian To German To Greek To Gujarati To Haitian Creole To Hausa To Hebrew To Hindi To Hmong To Hungarian To Icelandic To Igbo To Indonesian To Irish To Italian To Japanese To Javanese To Kannada To Kazakh To Khmer To Korean To Kurdish To Kyrgyz To Lao To Latin To Latvian To Lithuanian To Luxembourgish To Macedonian To Malagasy To Malay To Malayalam To Maltese To Maori To Marathi To Mongolian To Burmese To Nepali To Norwegian To Polish To Portuguese To Punjabi To Romanian To Russian To Samoan To Scots Gaelic To Serbian To Sesotho To Shona To Sinhala To Slovak To Slovenian To Somali To Spanish To Sundanese To Swahili To Swedish To Tajik To Tamil To Telugu To Thai To Turkish To Ukrainian To Urdu To Uzbek To Vietnamese To Welsh To Xhosa To Yiddish To Yoruba To Zulu English French Afrikaans Word Albanian Word Arabic Word Bengali Word Chinese Word Croatian Word Czech Word Danish Word Dutch Word English Word Finnish Word French Word German Word Greek Word Hindi Word Hungarian Word Icelandic Word Indonesian Word Italian Word Japanese Word Korean Word Latin Word Malay Word Malayalam Word Marathi Word Nepali Word Norwegian Word Polish Word Portuguese Word Romanian Word Russian Word Serbian Word Slovak Word Spanish Word Swahili Word Swedish Word Tamil Word Telugu Word Thai Word Turkish Word Ukrainian Word Uzbek Word Vietnamese Word Welsh Word All words 2-letter words 3-letter words 4-letter words 5-letter words 6-letter words 7-letter words 8-letter words 9-letter words 10-letter words 11-letter words 12-letter words 13-letter words 14-letter words Plural of Singular of Past tense of Present tense of Verb for Adjective for Adverb for Noun for Meaning of name Origin of name Names meaning Names starting with Names of origin preclinical Use * for blank tiles (max 2) Advanced Search Advanced Search Use * for blank spaces Advanced Search Advanced Word Finder See Also Words that rhyme with preclinical Use our Sentence Generator Nearby Words preclearance precisionist precision precising precisian preciseness preclude precluded precludes precluding preclusion preclusive 11-letter Words Starting With p pr pre prec precl precli preclin preclini preclinic preclinica