| The shortage of human donor pancreases for islet cell transplantation has led to a search for alternative sources of islet cells. |
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| The pancreases and muscles of the pups born to restricted-diet mothers were much smaller than those of pups born to mothers on normal diets. |
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| Likewise, in 1988 approximately 580 pancreases were recovered, but in 2008 some 1,830 were recovered. |
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| Eventually, extracts from pig and cow pancreases created a sufficient and reliable supply of insulin. |
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| Recently, researchers have found macrophages in the pancreases of people with Type II diabetes. |
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| They then measured the sizes of the brains, pancreases and muscles of the pups that were born. |
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| But there are, at present, only several thousand donated pancreases each year in the United States. |
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| Organ xenotransplants could include whole hearts, lungs, livers, kidneys or pancreases. |
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| Approximately 88,000 people are on the national organ transplant waiting list, waiting for kidneys, livers, pancreases, intestines, hearts and lungs. |
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| He established one of the first licensed fetal-tissue banks in the country, collecting pancreases for research that may lead to cures for incurable diseases. |
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| While today's insulins are produced in large volumes through biotechnological processes, in the early days, insulin was derived from cow and pig pancreases and was produced in limited amounts. |
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| In Canada, where there are about 300 donor pancreases a year, fewer than 100 of the 100,000 diabetics who could potentially benefit from the procedure can receive treatment annually. |
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| There aren't enough donor pancreases for transplant. |
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| And products of tissue engineering cultivated in vitro, have recently become available: skin and blood vessels, and before long, livers, pancreases and corneas. |
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| Preliminary research suggests the selection criteria for donor pancreases can be expanded to include donors with a slightly elevated A1c, and could measurably increase the supply of islets available for transplantation. |
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| This was confirmed by the studies of German researchers Josef von Mehring and Oskar Minkowski in 1889, who were removing pancreases for other reasons but observed that this led to intense glycosuria and diabetes. |
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| In a typical year, 345 Ontarians are blessed with replacement kidneys, 41 Albertans get new livers, 15 British Columbians win a second chance at life with a new heart, and up to a dozen pancreases are transplanted in Quebec. |
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| Replacements for some diabetics' missing insulin-producing cells might be found in the patients' own pancreases, a new study in mice suggests. |
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| Type 1 diabetics have high blood sugar levels because their pancreases cannot produce sufficient quantities of the hormone insulin. |
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| The major limiting step in offering islet transplantation to more diabetic patients is the supply of islets, which is limited because in Canada there are on average only 400 pancreases available per year for islet isolations. |
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