| Thus, suppression of the cut mutant wing phenotype is most likely due to the overexpression of Lola. |
|
| This pattern of expression suggests that cyclin DI overexpression may be an early event in endometrial carcinogenesis. |
|
| Again, the types of cells affected correlate with the time of overexpression. |
|
| The syndrome represents an overexpression of the normal ovulatory process described in normal pregnancy. |
|
| Mutation and overexpression of labial result in altered homeotic gene expression in the tritocerebrum. |
|
| The yucca phenotype derives from overexpression of a flavin monooxygenase like enzyme that oxidizes tryptamine to N-hydroxyl-tryptamine in vitro. |
|
| The control of its overexpression may constitute a therapeutic option for these diseases. |
|
| Analysis of human skin samples of patients suffering from nickel allergy demonstrated an overexpression of CXCR3 ligands and CCL20 chemokines. |
|
| Finally, we also studied compensation of dysferlin by myoferlin overexpression in muscle. |
|
| Dr. Gaboury then became interested in developing molecular tools to assay the overexpression of the HER-2 oncogene. |
|
| Interestingly, overexpression of the functional wild-type HA-Mcm7p from an episome or an integrated allele was toxic for normal cell growth and viability. |
|
| In addition, the overexpression of HER2 was also observed in stomach cancer. |
|
| Therefore, we tested the tryptophan catabolites, picolinic acid and quinolinic acid to see if they could reproduce the effects of IDO overexpression. |
|
| The overexpression of autolysin genes involved in the restructuring of the cell wall further confirms these findings. |
|
| A method for increasing secretion of an overexpressed gene product from a host cell which comprises effecting the overexpression of at least one hsp70 chaperone protein. |
|
| Proviral rearrangements and overexpression of a new cellular gene in myeloblastosis-associated virus type 1-induced nephroblastomas. |
|
| Patients with Down's syndrome may have overexpression of AIRE gene because of disomic homozygosity. |
|
| We observed that the Pax6 protein is localised to chromosomes and overexpression of the protein induces a defect in mitosis: incomplete chromatid separation results in defective mitosis at the onset of anaphase. |
|
| Breast cancers, for example, are regularly tested for the overexpression of HER-2, and only those patients whose cancers have the protein are treated with Herceptin. |
|
| Herceptin is a drug designed to control the overexpression of the HER2 protein in a breast tumour, a protein whose growth runs out of control in 25 to 30percentnt of cases. |
|
|
|
| Additional data indicates that overexpression of YB-1 in tumor cells generates several chemoresistance signatures apparent by microarray expression analyses. |
|
| While neither study reached its primary endpoint, good tolerability and encouraging trends towards higher activity for patients with high levels of EpCAM overexpression and treated at higher doses were observed. |
|
| This hypothesis is supported by the fact that overexpression of DNAJB2 facilitates the elimination of toxic protein aggregates in the nervous system. |
|
| Method for lowering the content of nitrates stored in a plant, characterized in that an overexpression of nitrate reductase is induced in the plant. |
|
| Calmodulin is a ubiquitous calcium signaling messenger and its overexpression leads to unregulated cell growth. |
|
| Abnormal overexpression of mastocytes in skin biopsies of fibromyalgia patients. |
|
| Importantly, overexpression of WASP in trc mutants and transheterozygotes of trc and Tsc2 suppressed their synaptic overgrowth phenotypes. |
|
| Insulin-like growth factor-I receptor overexpression mediates cellular radioresistance and local breast cancer recurrence after lumpectomy and radiation. |
|
| Forced overexpression of Axl in LNCaP cells decreased metformin and taxotere sensitivity and knockdown of Axl in resistant cells increased sensitivity to these drugs. |
|
| Cyclin D1 overexpression in primary hypopharyngeal carcinomas. |
|
| Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. |
|
