He blamed the party's misfortunes on poor leadership.
Her injury was a great misfortune.
It was my misfortune to be chosen first.
She endured her misfortune without complaint.
But as fortune, or misfortune, would have it, tickets weren't selling like hot cakes, saving heaps of fans from heaps of heartache.
The recent misfortune of a search engine optimisation firm has lifted the lid on shadowy tactics in this controversial industry.