| Regardless of the implement used, the prosector will perform the best microdissection while looking through the eyepieces of the microscope. |
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| However, interest in this general technology has mushroomed recently with the development of laser capture microdissection. |
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| All samples were subjected to histological examination prior to microdissection. |
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| We are also using laser capture microdissection and label free LC-S technologies to profile protein expression in blood capillaries isolated from normal and malignant breast tissues. |
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| Isolation of different cell types by laser capture microdissection is being used to identify distinct signatures for early stage disease, metastatic lesions, tumour stroma and tumour vasculature. |
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| Some reagents are proposed to inhibit RNAses but they usually strongly alter morphology which severely makes tissue structure and cell recognition difficult while it is a crucial argument for laser microdissection. |
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| It is a very powerful tool to explore tissues to discover and to validate new therapeutic markers identified by molecular methods such as DNA chips, mass spec, Q-PCR, laser microdissection. |
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| As a first, ALPHELYS will introduce the new ARCTURUS solutions for laser microdissection with the latest generation of Instruments VERITAS and the new Paradise Kit for RNA extraction from fixed tissues. |
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| Adhering to the PSA® tape, the tissue section stays perfectly in place until mounting for an ideal contact between Arcturus Pixcell® capsure and the section for an improvement microdissection accuracy. |
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| Subsequently, samples are clustered for microdissection on a weekly basis. |
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| The lateral wall was kept intact during microdissection. |
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| Microdissection was performed using the Leica LMD 6000 microdissector, to obtain the whole crypts, including pericryptal areas, for each sample. |
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