This iatrogenic hyperpigmentation is associated with lipofuscin rather than melanin deposits. |
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Studies performed on cultured mammalian cell lines demonstrate that most of the cell fluorescence arises from reduced pyridine nucleotides, flavins, and lipofuscin. |
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Electron microscopy showed membrane-bound vacuoles that contained reticulogranular and flocculent material, dense bodies, lamellar inclusions, and lipofuscin. |
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Changes in nerve cells of the nucleus basalis of Meynert in Alzheimer's disease and their relationship to ageing and to the accumulation of lipofuscin pigment. |
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