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Sentence Examples Causes of intestinal obstruction include volvulus, intussusception, incarcerated hernia, and postoperative adhesions. Most infants who are treated within the first 24 hours recover completely from an intussusception with no problems. A water soluble enema performed on the day of admission did not demonstrate an intussusception. These new-generation vaccines are not without risk and at least one, a tetravalent rotavirus vaccine, has been discontinued due to its association with bowel intussusception. We describe a case of intussusception of the terminal ileum, accompanied by necrotizing lymphadenitis with extensive infarction in a 4-year-old child with thalassemia major. Sometimes the intussusception is eliminated by administration of a barium enema. The increased incidence of intussusception associated with an earlier vaccine doesn't appear to be a problem, although surveillance is ongoing. These would be injected rather than swallowed and would be unlikely to carry any risk of intussusception. Following the 1-year safety followup period, 4 cases of intussusception were reported in children who had received placebo during the study. In postmarketing surveillance after distribution of 23 million doses of Rotarix, there has also been no increased risk of intussusception. The risk of intussusception has been evaluated in a large safety trial conducted in Latin America and Finland where 63,225 infants were enrolled. Death from intussusception is rare if people have prompt access to treatment. In 1999, for instance, doctors reported cases of intussusception, a sometimes deadly intestinal disorder, in a few infants given a new vaccine against rotavirus. It was due to this experience with RotaShield that new rotavirus vaccines required extremely large and carefully performed studies for the assessment of safety, particularly for the relatively rare event of intussusception. But in October last year the vaccine was withdrawn by its marketing company, Wyeth-Lederle, after it was linked with cases of intussusception, a serious and occasionally fatal blockage of the bowel, in U. S. infants. An intestinal obstruction was suspected based on radiographic findings, and an ileo-ceco-rectal intussusception was confirmed by coelioscopy. There were no confirmed cases of intussusception during the 42-day period after dose one, and there was no clustering of cases among vaccine recipients at any time period after any dose. Similarly to other studies, we did not consider an increased risk for intussusception or any other adverse events after rotavirus vaccination. Oddly enough the barium enema may cause the intussusception to right itself. Merck designed this study to be large enough to provide a meaningful evaluation of efficacy and safety of its vaccine with respect to intussusception. Show More Sentences Active surveillance was employed to identify potential cases of intussusception at days 7, 14, and 42 after each dose and every 6 weeks thereafter for 1 year after dose one. Researchers estimate that at least 60,000 participants will be needed, and possibly as many as 1 million, for trials to be able to pick up the risk of intussusception. This would provide baseline data on rates of intussusception that will be useful for assessing the safety of a vaccine following its introduction. Once in the small intestine, the balloon served as the lead point with peristalsis generating the intussusception. The rapid response postlicensure to reports of intussusception following RotaShield immunization in the United States in 1999 and the MMR vaccine in Canada noted above demonstrates how effectively these systems work. In small mammals, intussusception may be caused by enteritis, prokinetic drugs, or exercise, or it may be an agonal event. Infants with active gastrointestinal illness, chronic diarrhea or growth retardation, or a history of congenital abdominal disorders or intussusception were not to be included in the clinical studies. The first such vaccine, called RotaShield, was approved for use in the United States in 1998 and withdrawn a year later after it was linked with rare cases of intussusception, or bowel obstruction. I said would I be covered for intussusception, a folding of the bowel? We rushed to the emergency room at Children's Hospital, where a new surgical resident examined him, ordered X-rays and blood tests and made the correct diagnosis: an intussusception, an intestinal obstruction. Immediately following the scan, a therapeutic contrast enema was administered multiple times in an attempt to reduce the intussusception but was unsuccessful. Examples from Classical Literature In intussusception not relieved by medical means the propriety of abdominal section is questionable. Stools composed almost wholly of mucus and streaked with blood are the rule in dysentery, ileocolitis, and intussusception. It is not a growth by accretion, as in crystallization, but by intussusception, as in life. In children difficulty of diagnosis may arise as between dysentery and intussusception. In this case the paretic segment forms the outer or receiving layer of the intussusception. The symptoms of intussusception generally come on suddenly, and indicate both intestinal obstruction and inflammation. A colloid globule suspended in a salt solution in which it is not dissolved may grow by intussusception. Severe straining occurs in some instances of intussusception, and when this occurs it should receive due credit. The most common variety of intussusception is the ileo-ccal. The mechanism of intussusception is probably not always the same. In adults, delay in diagnosis and definitive treatment may be a direct result of common symptomatology between postoperative ileus and intussusception. Find more words! 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What is the adjective for intussusception? What is the noun for intussusception? Use our Sentence Generator Nearby Words inturned in turn in turmoil in tune intune intumescent intussusceptive in two minds Inuit Inuits Inuk inukshuk 15-letter Words Starting With i in int intu intus intuss intussu intussus intussusc intussusce intussuscep