One strategy to improve the immune reaction is to make what are called heteroclitic antigen variants. |
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This server provides a computerised approach to the design of heteroclitic peptides, using the additive method to calculate affinities. |
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However, this opening is not in the direction of complication nor of the accumulation of heteroclitic references. |
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The most monomaniacal and extreme of Berlin Dadaists, Johannes Baader is to Dada what Byron is to Romanticism, ultimately inassimilable and heteroclitic among heteroclites. |
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Yet although the themes may be well known, Frame continues to surprise the reader by her heteroclitic form of expression. |
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Surprisingly, we show that heteroclitic peptides designed with optimal MHC binding motifs do not always form pMHCs that are substantially more stable than their wildtype progenitors. |
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Our results further highlight the fact that heteroclitic peptide-based immune interventions require careful evaluation to ensure that wildtype antigen specificity is maintained in vivo. |
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One strategy to generate T-cell responses to tumors is to alter subdominant epitopes through substitution of amino acids that are optimal anchors for specific MHC molecules, termed heteroclitic epitopes. |
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In general, the improved stability of these heteroclitic complexes has been inferred from their improved immunogenicity but has not been formally assessed. |
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Except for the Italian and Romanian heteroclitic nouns, other major Romance languages have no trace of neuter nouns, but still have neuter pronouns. |
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