| Several forms of cancer involve the inactivation of the apoptotic process, thus enabling the cancer cells to continue to proliferate. |
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| There were no obviously enucleate cells, no apoptotic bodies, and no evidence of dead crushed cells. |
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| In the phagosomes, lysosomes are activated and fuse with the apoptotic bodies, bringing on their dissolution. |
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| They are thought to represent lysosomal globules, composed of apoptotic bodies phagocytosed by the tumor cells. |
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| In the first part of this review, the biochemistry and physiology of apoptotic pathways and its regulators are discussed. |
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| We recommend further evaluation using additional special techniques for detecting apoptotic leukocytes. |
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| This removal of apoptotic neutrophils by macrophage phagocytosis is a critical process for the resolution of inflammation. |
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| In addition, these ligands markedly upregulated production of CD36, a scavenger receptor that regulates phagocytosis of apoptotic neutrophils. |
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| Clearance of apoptotic cells by phagocytes is crucial in maintaining tissue homeostasis. |
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| The test was used to compare the number of apoptotic cells in unstimulated versus stimulated lymphocytes. |
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| An altered apoptotic response represents a pivotal feature of cancer, contributing to carcinogenesis and resistance to therapy. |
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| These results suggest that inhibition of p70 S6K is not causatively related to the apoptotic response. |
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| During embryogenesis and metamorphosis, plasmatocytes are involved in the clearance of apoptotic cells and histolytic debris. |
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| Digitoxin in nontoxic concentrations induces apoptotic cell death in Jurkat T cells in vitro. |
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| Loss of matrix attachment of cultured epithelial cells activates a caspase-mediated apoptotic program known as anoikis. |
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| They concluded that coprisin could be a model molecule for a large family of novel AMPs possessing apoptotic activities. |
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| Afonso et al observed that human necrotic, but not apoptotic, neutrophils induced in vitro leishmanicidal activity mediated by macrophages. |
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| By turning off the apoptotic pathway, some cancer cells may become intrinsically radioresistant. |
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| Motoneurons appears to die by apoptotic cell death during this time, different from necrotic cell death. |
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| Interestingly, BFDV antigens were detected in the nuclei and cytoplasm of such apoptotic cells. |
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| Microscale autoradiographic method for the qualitative and quantitative analysis of apoptotic DNA fragmentation. |
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| There were scattered apoptotic cells, few binucleate cells, and multifocal areas of necrosis within the mass. |
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| Focal necrosis may be seen, and mitoses and apoptotic bodies are usually numerous. |
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| Neuronal cell death has been shown to occur by apoptotic, necrotic and so-called atypical cell death mechanisms. |
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| Hedgehog morphogens are associated with MPs shed from the plasma membrane of apoptotic stimulated T cells. |
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| The neoplasm, which had apoptotic bodies and necrobiosis, also invaded the full thickness of the skin, and the epidermis was very thin. |
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| Supravital exposure to propidium iodide identities apoptotic cells in the absence of nucleosomal DNA fragmentation. |
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| The apoptotic features noted included, chromatin condensation, nuclear pyknosis and nuclear fragmentation. |
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| Apoptotic keratinocytes with condensed eosinophilic cytoplasm, with or without pyknotic nuclei, are also appreciated. |
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| In contrast, POL-treated MCF-7 cells showed typical apoptotic features, including chromatin condensation and margination at the nuclear periphery. |
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| Other cellular vesicles include argosomes, blebs, and apoptotic bodies. |
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| Caspase-3 is one of the principal caspases found in apoptotic cells. |
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| Intracellular nuclease activity in both apoptotic and necrotic cells in a particular organ affect the degree of DNA degradation found in body fluids. |
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| Apoptotic death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors. |
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| Apoptotic bodies also contain miRNAs, although it is not clear yet whether these miRNAs are specifically or nonspecifically packaged into these bodies. |
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