| Leber congenital amaurosis is an inherited disease that is believed to cause up to 20 percent of all cases of childhood blindness. |
|
| Another popular writer of detective stories was Ernest Bramah, creator of the blind detective Max Carrados, sufferer of amaurosis. |
|
| Other visual symptoms may include amaurosis fugax, diplopia and partial loss of vision. |
|
| Gene therapy has already proved effective in restoring sight in puppies blinded by Leber's congenital amaurosis, a genetic disease. |
|
| His laboratory also collaborates on gene therapy projects and conducts its own research such as gene therapy with AAV in Leber's congenital amaurosis, a rare disease of the retina. |
|
| The study, reported in the journal Lancet, involved five children and seven adults, from Belgium, Italy and the United states, with a type of Leber's congenital amaurosis, rare but serious congenital retinal diseases. |
|
| This combined approach has allowed us to discover 5 new genes thusfar, including CEP290, LCA5 and LCA3 for Leber congenital amaurosis and RP25 and TOPORS1 for retinitis pigmentosa. |
|
| In the case of Leber's congenital amaurosis, viruses carrying the correct gene can be injected directly into the retina where they will infect retinal cells. |
|
