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Noun Something that is difficult or impossible to understand or explain mystery enigma puzzle riddle conundrum secret question paradox poser problem puzzler quandary puzzlement why abstruseness abstrusity bewilderment crux mystification stumper teaser brainteaser braintwister charade head-scratcher perplexity roun rune stickler twister question mark closed book brain-teaser tough nut to crack mind-boggler mind-twister sixty-four-thousand-dollar question sixty-four dollar question cryptogram complexity dilemma challenge mindboggler knotty question tough proposition cliffhanger Gordian knot intricacy complication maze rebus koan Chinese puzzle snarl difficulty cruncher difficult question difficult proposition how-do-you-do awkward problem can of worms toughie hard nut to crack vexed question brain-twister tough one knotty problem facer inscrutability inscrutableness secrecy occult subtlety obscurity ambiguity thriller grabber oracle chiller whodunit sphinx unknown tickler food for thought mind-bender inexplicableness mystique quiz magic anybody's guess anyone's guess sixty-four thousand dollar question imponderable involvement fix inextricability obfuscation contradiction dichotomy incongruity inconsistency conflict anomaly oddity oxymoron absurdity antinomy catch irony juxtaposition error shocker self-contradiction catch-22 contradiction in terms reverse psychology “The mechanism of adaptation remains a fundamental unsolved problem in evolutionary biology.” Find more words! 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