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Using one's left hand in preference to, or more skillfully than, one's right
“As a left-handed guitarist, Jimi would play a right-handed guitar upside-down.”
Pertaining to the left side of something
“Jordy sits right across from us, on the left-handed side of the dining table.”
Characterized by a lack of sincerity
“There is nothing Mosley takes for granted about Wright, giving what might be a left-handed compliment in saying Winky sometimes fights to the level of his competition.”
Clumsy or awkward in the use of one's hands
“Sinatra's left-handed attempt at characterization not only harms the picture immeasurably but indicates an alarming lack of professionality.”
Turning or spiraling from right to left
“The left-handed clock is surprisingly easy to read if you don't think too hard about it.”
Insincere or hypocritical in nature
Left-handed people, taken as a whole
“Dysphasia following surgery on the right hemisphere was not significantly more frequent in the left-handed than in the right-handed.”
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